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MCL1 is critical for mitochondrial function and autophagy in the heart
MCL1 (myeloid cell leukemia sequence 1 [BCL2-related]) is an anti-apoptotic BCL2 family protein that is upregulated in several human cancers. In malignancies, overexpression of MCL1 promotes cell survival and confers chemotherapeutic resistance. MCL1 is also highly expressed in normal myocardium, bu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4028340/ https://ncbi.nlm.nih.gov/pubmed/24165322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.26168 |
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