A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts
An in vitro system that recapitulates the in vivo effect of AU-rich elements (AREs) on mRNA deadenylation has been developed from Xenopus activated egg extracts. ARE-mediated deadenylation is uncoupled from mRNA body decay, and the rate of deadenylation increases with the number of tandem AUUUAs. A...
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| Опубліковано в:: | Genes Dev |
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| Автори: | , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Cold Spring Harbor Laboratory Press
2001
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.872201 |
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