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A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts

An in vitro system that recapitulates the in vivo effect of AU-rich elements (AREs) on mRNA deadenylation has been developed from Xenopus activated egg extracts. ARE-mediated deadenylation is uncoupled from mRNA body decay, and the rate of deadenylation increases with the number of tandem AUUUAs. A...

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Detalles Bibliográficos
Main Authors: Voeltz, Gia K., Ongkasuwan, Julina, Standart, Nancy, Steitz, Joan A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC312653/
https://ncbi.nlm.nih.gov/pubmed/11274061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.872201
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