A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts

An in vitro system that recapitulates the in vivo effect of AU-rich elements (AREs) on mRNA deadenylation has been developed from Xenopus activated egg extracts. ARE-mediated deadenylation is uncoupled from mRNA body decay, and the rate of deadenylation increases with the number of tandem AUUUAs. A...

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Bibliografische Detailangaben

Veröffentlicht in:	Genes Dev
Hauptverfasser:	Voeltz, Gia K., Ongkasuwan, Julina, Standart, Nancy, Steitz, Joan A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2001
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312653/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.872201
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