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Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action

The current standard of care for hepatitis C virus (HCV)-infected patients consists of lengthy treatment with interferon and ribavirin. To increase the effectiveness of HCV therapy, future regimens will incorporate multiple direct-acting antiviral (DAA) drugs. Recently, the HCV-encoded NS5A protein...

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Main Authors: Targett-Adams, Paul, Graham, Emily J. S., Middleton, Jenny, Palmer, Amy, Shaw, Stephen M., Lavender, Helen, Brain, Philip, Tran, Thien Duc, Jones, Lyn H., Wakenhut, Florian, Stammen, Blanda, Pryde, David, Pickford, Chris, Westby, Mike
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126509/
https://ncbi.nlm.nih.gov/pubmed/21507963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00215-11
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