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In-cell click labelling of small molecules to determine subcellular localisation

Small molecule fluorometric boron dipyrromethene probes were developed to bind hepatitis C virus-encoded NS5A protein and aid subcellular distribution studies. These molecules did not co-locate with NS5A, therefore alternative ‘silent’ azide reporters were used to obtain a more relevant picture of t...

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Detalhes bibliográficos
Main Authors: Jones, Lyn H., Beal, David, Selby, Matthew D., Everson, Owen, Burslem, George M., Dodd, Peter, Millbank, Jared, Tran, Thien-Duc, Wakenhut, Florian, Graham, Emily J. S., Targett-Adams, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077213/
https://ncbi.nlm.nih.gov/pubmed/22096474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-010-0047-1
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