Načítá se...

Click-Addressable Cassette for Photoaffinity Labeling

[Image: see text] A small molecule 1 was designed to contain an alkyne, a trifluoromethyl phenyldiazirine, and a free piperidine-NH for facile conjugation to protein binding ligands. This “cassette” 1 was synthesized via a relatively direct route involving only routine steps. In this proof-of-concep...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:ACS Med Chem Lett
Hlavní autoři: Zhao, Bosheng, Burgess, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2018
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807873/
https://ncbi.nlm.nih.gov/pubmed/29456805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00516
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!