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Inhibition of Dengue Virus by Targeting Viral NS4B Protein
We report a novel inhibitor that selectively suppresses dengue virus (DENV) by targeting viral NS4B protein. The inhibitor was identified by screening a 1.8-million-compound library using a luciferase replicon of DENV serotype 2 (DENV-2). The compound specifically inhibits all four serotypes of DENV...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3194949/ https://ncbi.nlm.nih.gov/pubmed/21865382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05468-11 |
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