Biological Effects and Use of PrP(Sc)- and PrP-Specific Antibodies Generated by Immunization with Purified Full-Length Native Mouse Prions

The prion agent is the infectious particle causing spongiform encephalopathies in animals and humans and is thought to consist of an altered conformation (PrP(Sc)) of the normal and ubiquitous prion protein PrP(C). The interaction of the prion agent with the immune system, particularly the humoral i...

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Autores principales: Petsch, Benjamin, Müller-Schiffmann, Andreas, Lehle, Anna, Zirdum, Elizabeta, Prikulis, Ingrid, Kuhn, Franziska, Raeber, Alex J., Ironside, James W., Korth, Carsten, Stitz, Lothar
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126253/
https://ncbi.nlm.nih.gov/pubmed/21345946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02467-10
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