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Biological Effects and Use of PrP(Sc)- and PrP-Specific Antibodies Generated by Immunization with Purified Full-Length Native Mouse Prions
The prion agent is the infectious particle causing spongiform encephalopathies in animals and humans and is thought to consist of an altered conformation (PrP(Sc)) of the normal and ubiquitous prion protein PrP(C). The interaction of the prion agent with the immune system, particularly the humoral i...
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Auteurs principaux: | , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Microbiology
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3126253/ https://ncbi.nlm.nih.gov/pubmed/21345946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02467-10 |
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