Assembly of Alphavirus Replication Complexes from RNA and Protein Components in a Novel trans-Replication System in Mammalian Cells

For positive-strand RNA viruses, the viral genomic RNA also acts as an mRNA directing the translation of the replicase proteins of the virus. Replication takes place in association with cytoplasmic membranes, which are heavily modified to create specific replication compartments. Here we have expres...

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Bibliografische gegevens
Hoofdauteurs: Spuul, Pirjo, Balistreri, Giuseppe, Hellström, Kirsi, Golubtsov, Andrey V., Jokitalo, Eija, Ahola, Tero
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2011
Onderwerpen:
Genome Replication and Regulation of Viral Gene Expression
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126202/
https://ncbi.nlm.nih.gov/pubmed/21389137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00085-11
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