Assembly of Alphavirus Replication Complexes from RNA and Protein Components in a Novel trans-Replication System in Mammalian Cells

For positive-strand RNA viruses, the viral genomic RNA also acts as an mRNA directing the translation of the replicase proteins of the virus. Replication takes place in association with cytoplasmic membranes, which are heavily modified to create specific replication compartments. Here we have expres...

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Main Authors: Spuul, Pirjo, Balistreri, Giuseppe, Hellström, Kirsi, Golubtsov, Andrey V., Jokitalo, Eija, Ahola, Tero
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126202/
https://ncbi.nlm.nih.gov/pubmed/21389137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00085-11
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