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Assembly of Alphavirus Replication Complexes from RNA and Protein Components in a Novel trans-Replication System in Mammalian Cells

For positive-strand RNA viruses, the viral genomic RNA also acts as an mRNA directing the translation of the replicase proteins of the virus. Replication takes place in association with cytoplasmic membranes, which are heavily modified to create specific replication compartments. Here we have expres...

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Detalhes bibliográficos
Main Authors: Spuul, Pirjo, Balistreri, Giuseppe, Hellström, Kirsi, Golubtsov, Andrey V., Jokitalo, Eija, Ahola, Tero
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126202/
https://ncbi.nlm.nih.gov/pubmed/21389137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00085-11
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