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Targeting the Hedgehog pathway in cancer

The Hedgehog (Hh) pathway is a major regulator of many fundamental processes in vertebrate embryonic development including stem cell maintenance, cell differentiation, tissue polarity and cell proliferation. Constitutive activation of the Hh pathway leading to tumorigenesis is seen in basal cell car...

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Detalhes bibliográficos
Main Authors: Gupta, Sachin, Takebe, Naoko, LoRusso, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126020/
https://ncbi.nlm.nih.gov/pubmed/21789137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834010366430
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