Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

During the past decade, cancer stem cells (CSCs) have been increasingly identified in many malignancies. Although the origin and plasticity of these cells remain controversial, tumour heterogeneity and the presence of small populations of cells with stem-like characteristics is established in most m...

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Bibliographic Details
Published in:Nat Rev Clin Oncol
Main Authors: Takebe, Naoko, Miele, Lucio, Harris, Pamela Jo, Jeong, Woondong, Bando, Hideaki, Kahn, Michael, Yang, Sherry X., Ivy, S. Percy
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520755/
https://ncbi.nlm.nih.gov/pubmed/25850553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2015.61
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