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Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

During the past decade, cancer stem cells (CSCs) have been increasingly identified in many malignancies. Although the origin and plasticity of these cells remain controversial, tumour heterogeneity and the presence of small populations of cells with stem-like characteristics is established in most m...

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Podrobná bibliografie
Vydáno v:Nat Rev Clin Oncol
Hlavní autoři: Takebe, Naoko, Miele, Lucio, Harris, Pamela Jo, Jeong, Woondong, Bando, Hideaki, Kahn, Michael, Yang, Sherry X., Ivy, S. Percy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520755/
https://ncbi.nlm.nih.gov/pubmed/25850553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2015.61
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