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Targeting Notch signaling pathway in cancer: Clinical development advances and challenges
Notch signaling plays an important role in development and cell fate determination, and it is deregulated in human hematologic malignancies and solid tumors. This review includes a brief introduction of the relevant pathophysiology of Notch signaling pathway and primarily focuses on the clinical dev...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982918/ https://ncbi.nlm.nih.gov/pubmed/24076266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2013.09.005 |
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