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Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened
An essential role for Hedgehog (Hh) signaling in human cancer has been established beyond doubt. At present, targeting Hh signaling has mainly been investigated with SMO inhibitors. Unfortunately, resistance against currently used SMO inhibitors has already been observed in basal cell carcinoma (BCC...
Shranjeno v:
| izdano v: | Oncotarget |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Impact Journals LLC
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546439/ https://ncbi.nlm.nih.gov/pubmed/26053182 |
| Oznake: |
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