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Targeting the Hedgehog pathway in cancer

The Hedgehog (Hh) pathway is a major regulator of many fundamental processes in vertebrate embryonic development including stem cell maintenance, cell differentiation, tissue polarity and cell proliferation. Constitutive activation of the Hh pathway leading to tumorigenesis is seen in basal cell car...

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Bibliografski detalji
Glavni autori: Gupta, Sachin, Takebe, Naoko, LoRusso, Patricia
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126020/
https://ncbi.nlm.nih.gov/pubmed/21789137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834010366430
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