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Targeting the Hedgehog pathway in cancer

The Hedgehog (Hh) pathway is a major regulator of many fundamental processes in vertebrate embryonic development including stem cell maintenance, cell differentiation, tissue polarity and cell proliferation. Constitutive activation of the Hh pathway leading to tumorigenesis is seen in basal cell car...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gupta, Sachin, Takebe, Naoko, LoRusso, Patricia
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126020/
https://ncbi.nlm.nih.gov/pubmed/21789137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834010366430
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