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Nucleotidylation of Unsaturated Carbasugar in Validamycin Biosynthesis

Validamycin A is a member of microbial-derived C(7)N-aminocyclitol family of natural products that is widely used as crop protectant and the precursor of the antidiabetic drug voglibose. Its biosynthetic gene clusters have been identified in several Streptomyces hygroscopicus strains, and a number o...

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Autori principali: Yang, Jongtae, Xu, Hui, Zhang, Yirong, Bai, Linquan, Deng, Zixin, Mahmud, Taifo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124559/
https://ncbi.nlm.nih.gov/pubmed/20981366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ob00475h
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