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Nucleotidylation of Unsaturated Carbasugar in Validamycin Biosynthesis

Validamycin A is a member of microbial-derived C(7)N-aminocyclitol family of natural products that is widely used as crop protectant and the precursor of the antidiabetic drug voglibose. Its biosynthetic gene clusters have been identified in several Streptomyces hygroscopicus strains, and a number o...

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Main Authors: Yang, Jongtae, Xu, Hui, Zhang, Yirong, Bai, Linquan, Deng, Zixin, Mahmud, Taifo
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124559/
https://ncbi.nlm.nih.gov/pubmed/20981366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ob00475h
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