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Alternative Epimerization in C(7)N-aminocyclitol Biosynthesis is Catalyzed by ValD, a Large Protein of the Vicinal Oxygen Chelate Superfamily
Gene valD, encodes a large Vicinal Oxygen Chelate (VOC) superfamily protein, has been identified in the validamycin biosynthetic gene cluster. Inactivation of valD significantly reduced validamycin A production, which was fully restored with the full-length valD and partially restored with either N-...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737586/ https://ncbi.nlm.nih.gov/pubmed/19477421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.04.006 |
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