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Catalytic Analysis of the Validamycin Glycosyltransferase (ValG) and Enzymatic Production of 4″-epi-Validamycin A
ValG is a glycosyltransferase (GT) that is responsible for the glucosylation of validoxylamine A to validamycin A. To explore the potential utilization of ValG as a tool for the production of validamycin analogs, a number of nucleotidyldiphosphate-sugars were evaluated as alternative substrates for...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574543/ https://ncbi.nlm.nih.gov/pubmed/18563934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np800185k |
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