Catalytic Analysis of the Validamycin Glycosyltransferase (ValG) and Enzymatic Production of 4″-epi-Validamycin A

ValG is a glycosyltransferase (GT) that is responsible for the glucosylation of validoxylamine A to validamycin A. To explore the potential utilization of ValG as a tool for the production of validamycin analogs, a number of nucleotidyldiphosphate-sugars were evaluated as alternative substrates for...

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Bibliographic Details
Main Authors: Xu, Hui, Minagawa, Kazuyuki, Bai, Linquan, Deng, Zixin, Mahmud, Taifo
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574543/
https://ncbi.nlm.nih.gov/pubmed/18563934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np800185k
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