Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

5-hydroxymethylcytosine (5hmC) is a modified base present at low levels in diverse cell types in mammals(1–5). 5hmC is generated by the TET family of Fe(II) and 2-oxoglutarate-dependent enzymes through oxidation of 5-methylcytosine (5mC)(1,2,4–7). 5hmC and TET proteins have been implicated in stem c...

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Bibliografiset tiedot
Päätekijät: Pastor, William A., Pape, Utz J., Huang, Yun, Henderson, Hope R., Lister, Ryan, Ko, Myunggon, McLoughlin, Erin M., Brudno, Yevgeny, Mahapatra, Sahasransu, Kapranov, Philipp, Tahiliani, Mamta, Daley, George Q., Liu, X. Shirley, Ecker, Joseph R., Milos, Patrice M., Agarwal, Suneet, Rao, Anjana
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124347/
https://ncbi.nlm.nih.gov/pubmed/21552279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10102
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