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The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing
BACKGROUND: We recently showed that enzymes of the TET family convert 5-mC to 5-hydroxymethylcytosine (5-hmC) in DNA. 5-hmC is present at high levels in embryonic stem cells and Purkinje neurons. The methylation status of cytosines is typically assessed by reaction with sodium bisulfite followed by...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811190/ https://ncbi.nlm.nih.gov/pubmed/20126651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008888 |
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