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The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine
5-Hydroxymethylcytosine (5hmc) is a newly discovered DNA base present at detectable levels in most mammalian cell types and tissues. It is generated by Tet-enzyme–mediated oxidation of 5-methylcytosine (5mc). 5hmc is important both because of its potential role in regulating gene expression and beca...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482405/ https://ncbi.nlm.nih.gov/pubmed/23018194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.104 |
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