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The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine

5-Hydroxymethylcytosine (5hmc) is a newly discovered DNA base present at detectable levels in most mammalian cell types and tissues. It is generated by Tet-enzyme–mediated oxidation of 5-methylcytosine (5mc). 5hmc is important both because of its potential role in regulating gene expression and beca...

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Autors principals: Pastor, William A, Huang, Yun, Henderson, Hope R, Agarwal, Suneet, Rao, Anjana
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482405/
https://ncbi.nlm.nih.gov/pubmed/23018194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.104
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