KRAS, NRAS, PIK3CA Exon 20, and BRAF Genotypes in Synchronous and Metachronous Primary Colorectal Cancers: Diagnostic and Therapeutic Implications

Targeted therapy of advanced colorectal carcinoma (CRC) necessitates KRAS genotyping. Because we were interested in diagnostic and therapeutic consequences, we studied the KRAS, NRAS, PIK3CA exon 20, and BRAF genotypes in synchronous and metachronous primary CRCs; in addition, we studied their avail...

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Detalhes bibliográficos
Main Authors: Balschun, Katharina, Haag, Jochen, Wenke, Ann-Kathrin, von Schönfels, Witigo, Schwarz, Nicolas T., Röcken, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123804/
https://ncbi.nlm.nih.gov/pubmed/21704278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2011.03.002
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