Inactivation Kinetics of a New Target of β-Lactam Antibiotics

Peptidoglycan is predominantly cross-linked by serine dd-transpeptidases in most bacterial species. The enzymes are the essential targets of β-lactam antibiotics. However, unrelated cysteine ld-transpeptidases have been recently recognized as a predominant mode of peptidoglycan cross-linking in Myco...

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Autores principales: Triboulet, Sébastien, Arthur, Michel, Mainardi, Jean-Luc, Veckerlé, Carole, Dubée, Vincent, NGuekam-Moumi, Angèle, Gutmann, Laurent, Rice, Louis B., Hugonnet, Jean-Emmanuel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123045/
https://ncbi.nlm.nih.gov/pubmed/21543331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.239988
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