Selective O-phosphitilation with nucleoside phosphoramidite reagents.

In contrast to tetrazole, pyridine hydrochloride/imidazole converts nucleoside phosphoramidites to intermediates that show a high preference for phosphitilating hydroxyl groups relative to nucleoside amino groups. Use of this activating agent and incorporation of a pyridine hydrochloride/aniline was...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Autores principales:	Gryaznov, S M, Letsinger, R L
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 1992
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1579488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.8.1879
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