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Selective O-phosphitilation with nucleoside phosphoramidite reagents.

In contrast to tetrazole, pyridine hydrochloride/imidazole converts nucleoside phosphoramidites to intermediates that show a high preference for phosphitilating hydroxyl groups relative to nucleoside amino groups. Use of this activating agent and incorporation of a pyridine hydrochloride/aniline was...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Gryaznov, S M, Letsinger, R L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 1992
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312301/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1579488/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.8.1879
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