Selective O-phosphitilation with nucleoside phosphoramidite reagents.
In contrast to tetrazole, pyridine hydrochloride/imidazole converts nucleoside phosphoramidites to intermediates that show a high preference for phosphitilating hydroxyl groups relative to nucleoside amino groups. Use of this activating agent and incorporation of a pyridine hydrochloride/aniline was...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1992
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1579488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.8.1879 |
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