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Characterization of a Mutant Escherichia coli Heat-Labile Toxin, LT(R192G/L211A), as a Safe and Effective Oral Adjuvant

Despite the fact that the adjuvant properties of the heat-labile enterotoxins of Escherichia coli (LT) and Vibrio cholerae (CT) have been known for more than 20 years, there are no available oral vaccines containing these molecules as adjuvants, primarily because they are both very potent enterotoxi...

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Autors principals: Norton, Elizabeth B., Lawson, Louise B., Freytag, Lucy C., Clements, John D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122563/
https://ncbi.nlm.nih.gov/pubmed/21288994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00538-10
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