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Characterization of a Mutant Escherichia coli Heat-Labile Toxin, LT(R192G/L211A), as a Safe and Effective Oral Adjuvant

Despite the fact that the adjuvant properties of the heat-labile enterotoxins of Escherichia coli (LT) and Vibrio cholerae (CT) have been known for more than 20 years, there are no available oral vaccines containing these molecules as adjuvants, primarily because they are both very potent enterotoxi...

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Detalhes bibliográficos
Main Authors: Norton, Elizabeth B., Lawson, Louise B., Freytag, Lucy C., Clements, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122563/
https://ncbi.nlm.nih.gov/pubmed/21288994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00538-10
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