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A Double Mutant Heat-Labile Toxin from Escherichia coli, LT(R192G/L211A), Is an Effective Mucosal Adjuvant for Vaccination against Helicobacter pylori Infection

Helicobacter pylori infection in the stomach is a common cause of peptic ulcer disease and is a strong risk factor for the development of gastric adenocarcinoma, yet no effective vaccine against H. pylori infection is available to date. In mice, mucosal vaccination with H. pylori antigens when given...

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書誌詳細
主要な著者: Sjökvist Ottsjö, Louise, Flach, Carl-Fredrik, Clements, John, Holmgren, Jan, Raghavan, Sukanya
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647992/
https://ncbi.nlm.nih.gov/pubmed/23439305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01407-12
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