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A Double Mutant Heat-Labile Toxin from Escherichia coli, LT(R192G/L211A), Is an Effective Mucosal Adjuvant for Vaccination against Helicobacter pylori Infection

Helicobacter pylori infection in the stomach is a common cause of peptic ulcer disease and is a strong risk factor for the development of gastric adenocarcinoma, yet no effective vaccine against H. pylori infection is available to date. In mice, mucosal vaccination with H. pylori antigens when given...

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Autors principals: Sjökvist Ottsjö, Louise, Flach, Carl-Fredrik, Clements, John, Holmgren, Jan, Raghavan, Sukanya
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647992/
https://ncbi.nlm.nih.gov/pubmed/23439305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01407-12
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