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A Double Mutant Heat-Labile Toxin from Escherichia coli, LT(R192G/L211A), Is an Effective Mucosal Adjuvant for Vaccination against Helicobacter pylori Infection

Helicobacter pylori infection in the stomach is a common cause of peptic ulcer disease and is a strong risk factor for the development of gastric adenocarcinoma, yet no effective vaccine against H. pylori infection is available to date. In mice, mucosal vaccination with H. pylori antigens when given...

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Bibliografski detalji
Glavni autori: Sjökvist Ottsjö, Louise, Flach, Carl-Fredrik, Clements, John, Holmgren, Jan, Raghavan, Sukanya
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647992/
https://ncbi.nlm.nih.gov/pubmed/23439305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01407-12
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