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Characterization of a Mutant Escherichia coli Heat-Labile Toxin, LT(R192G/L211A), as a Safe and Effective Oral Adjuvant

Despite the fact that the adjuvant properties of the heat-labile enterotoxins of Escherichia coli (LT) and Vibrio cholerae (CT) have been known for more than 20 years, there are no available oral vaccines containing these molecules as adjuvants, primarily because they are both very potent enterotoxi...

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Détails bibliographiques
Auteurs principaux: Norton, Elizabeth B., Lawson, Louise B., Freytag, Lucy C., Clements, John D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122563/
https://ncbi.nlm.nih.gov/pubmed/21288994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00538-10
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