Detection of Inferred CCR5- and CXCR4-Using HIV-1 Variants and Evolutionary Intermediates Using Ultra-Deep Pyrosequencing

The emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants is associated with accelerated disease progression. CXCR4-using variants are believed to evolve from CCR5-using variants, but due to the extremely low frequency at which transitional intermediate variants are often pre...

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Autores principales: Bunnik, Evelien M., Swenson, Luke C., Edo-Matas, Diana, Huang, Wei, Dong, Winnie, Frantzell, Arne, Petropoulos, Christos J., Coakley, Eoin, Schuitemaker, Hanneke, Harrigan, P. Richard, van 't Wout, Angélique B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121885/
https://ncbi.nlm.nih.gov/pubmed/21731496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002106
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