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Reconstructing the Dynamics of HIV Evolution within Hosts from Serial Deep Sequence Data
At the early stage of infection, human immunodeficiency virus (HIV)-1 predominantly uses the CCR5 coreceptor for host cell entry. The subsequent emergence of HIV variants that use the CXCR4 coreceptor in roughly half of all infections is associated with an accelerated decline of CD4+ T-cells and rat...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486858/ https://ncbi.nlm.nih.gov/pubmed/23133358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002753 |
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