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Impact of CCR5delta32 Host Genetic Background and Disease Progression on HIV-1 Intrahost Evolutionary Processes: Efficient Hypothesis Testing through Hierarchical Phylogenetic Models

The interplay between C-C chemokine receptor type 5 (CCR5) host genetic background, disease progression, and intrahost HIV-1 evolutionary dynamics remains unclear because differences in viral evolution between hosts limit the ability to draw conclusions across hosts stratified into clinically releva...

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Detalhes bibliográficos
Main Authors: Edo-Matas, Diana, Lemey, Philippe, Tom, Jennifer A., Serna-Bolea, Cèlia, van den Blink, Agnes E., van 't Wout, Angélique B., Schuitemaker, Hanneke, Suchard, Marc A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080134/
https://ncbi.nlm.nih.gov/pubmed/21135151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msq326
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