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HEK293T Cells Are Heterozygous for CCR5 Delta 32 Mutation
C-C chemokine receptor 5 (CCR5) is a receptor for chemokines and a co-receptor for HIV-1 entry into the target CD4+ cells. CCR5 delta 32 deletion is a loss-of-function mutation, resistant to HIV-1 infection. We tried to induce the CCR5 delta 32 mutation harnessing the genome editing technique, CRISP...
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Gepubliceerd in: | PLoS One |
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Hoofdauteurs: | , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Public Library of Science
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820142/ https://ncbi.nlm.nih.gov/pubmed/27042825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152975 |
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