Unique Interaction Pattern for a Functionally Biased Ghrelin Receptor Agonist

Based on the conformationally constrained d-Trp-Phe-d-Trp (wFw) core of the prototype inverse agonist [d-Arg(1),d-Phe(5),d-Trp(7,9),Leu(11)]substance P, a series of novel, small, peptide-mimetic agonists for the ghrelin receptor were generated. By using various simple, ring-constrained spacers conne...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Sivertsen, Bjørn, Lang, Manja, Frimurer, Thomas M., Holliday, Nicholas D., Bach, Anders, Els, Sylvia, Engelstoft, Maja S., Petersen, Pia S., Madsen, Andreas N., Schwartz, Thue W., Beck-Sickinger, Annette G., Holst, Birgitte
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121491/
https://ncbi.nlm.nih.gov/pubmed/21402696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173237
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk