Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

OBJECTIVE: Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through different signaling pathways. The nuclear BA receptor farnesoid X receptor (FXR) regulates pathways in BA, lipid, glucose, and energy metabolism, which become dysregulated in obesity. However, the role...

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Detalhes bibliográficos
Main Authors: Prawitt, Janne, Abdelkarim, Mouaadh, Stroeve, Johanna H.M., Popescu, Iuliana, Duez, Helene, Velagapudi, Vidya R., Dumont, Julie, Bouchaert, Emmanuel, van Dijk, Theo H., Lucas, Anthony, Dorchies, Emilie, Daoudi, Mehdi, Lestavel, Sophie, Gonzalez, Frank J., Oresic, Matej, Cariou, Bertrand, Kuipers, Folkert, Caron, Sandrine, Staels, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121443/
https://ncbi.nlm.nih.gov/pubmed/21593203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0030
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