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Early Treatment of Transient Focal Cerebral Ischemia with Bovine PEGylated Carboxy Hemoglobin Transfusion

The effect of transfusion of PEGylated hemoglobin (PEG-Hb) was evaluated in anesthetized rats subjected to 2 hours of focal cerebral ischemia and 1 day of reperfusion. PEG-Hb was stored in the carboxy state (PEG-COHb) to reduce autooxidation and increase the shelf life. Transfusion of 10 ml/kg of PE...

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Detalhes bibliográficos
Main Authors: Klaus, Judith A., Kibler, Kathleen K., Abuchowski, Abraham, Koehler, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121099/
https://ncbi.nlm.nih.gov/pubmed/20486873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10731199.2010.488635
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