Endothelin rather than 20-HETE contributes to loss of pial arteriolar dilation during focal cerebral ischemia with and without polymeric hemoglobin transfusion

Partial exchange transfusion with a cell-free hemoglobin (Hb) polymer during transient middle cerebral artery occlusion (MCAO) reduces infarct volume but fails to increase blood flow, as might be expected with the induced decrease in hematocrit. In ischemic brain, endothelin antagonists are known to...

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Detalhes bibliográficos
Main Authors: Cao, Suyi, Wang, Liang-Chao, Kwansa, Herman, Roman, Richard J., Harder, David R., Koehler, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Neurohumoral Control of Cardiovascular Function
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689832/
https://ncbi.nlm.nih.gov/pubmed/19261918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00003.2009
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