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Transfusion of hemoglobin-based oxygen carriers in the carboxy state is beneficial during transient focal cerebral ischemia

Exchange transfusion of large volumes of hemoglobin (Hb)-based oxygen carriers can protect the brain from middle cerebral artery occlusion (MCAO). Hb in the carboxy state (COHb) may provide protection at relatively low volumes by enhancing vasodilation. We determined whether transfusion of rats with...

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Bibliografiset tiedot
Päätekijät: Zhang, Jian, Cao, Suyi, Kwansa, Herman, Crafa, Daina, Kibler, Kathleen K., Koehler, Raymond C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2012
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544507/
https://ncbi.nlm.nih.gov/pubmed/23042910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01079.2012
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