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Transfusion of hemoglobin-based oxygen carriers in the carboxy state is beneficial during transient focal cerebral ischemia

Exchange transfusion of large volumes of hemoglobin (Hb)-based oxygen carriers can protect the brain from middle cerebral artery occlusion (MCAO). Hb in the carboxy state (COHb) may provide protection at relatively low volumes by enhancing vasodilation. We determined whether transfusion of rats with...

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Bibliografski detalji
Glavni autori: Zhang, Jian, Cao, Suyi, Kwansa, Herman, Crafa, Daina, Kibler, Kathleen K., Koehler, Raymond C.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544507/
https://ncbi.nlm.nih.gov/pubmed/23042910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01079.2012
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