Transfusion of Polynitroxylated Pegylated Hemoglobin Stabilizes Pial Arterial Dilation and Decreases Infarct Volume After Transient Middle Cerebral Artery Occlusion

BACKGROUND: Polynitroxylation of hemoglobin confers superoxide dismutase–mimetic and peroxidase activity and may protect from reperfusion injury in addition to facilitating oxygen transport. We determined whether transfusion of polynitroxylated PEGylated hemoglobin (PNPH) is protective in the rat fi...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Cao, Suyi, Zhang, Jian, Ma, Li, Hsia, Carleton J. C., Koehler, Raymond C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634295/
https://ncbi.nlm.nih.gov/pubmed/28899897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006505
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