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Salvage of focal cerebral ischemic damage by transfusion of high O(2)-affinity recombinant hemoglobin polymers in mouse
Cell-free hemoglobin solutions with high oxygen affinity might be beneficial for selectively delivering oxygen to ischemic tissue. A recombinant hybrid hemoglobin molecule was designed using the human α-subunit and the bovine β-subunit, with placement of surface cysteines to permit disulfide bond po...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1764455/ https://ncbi.nlm.nih.gov/pubmed/16424069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01374.2005 |
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