Chronic Losartan Administration Reduces Mortality and Preserves Cardiac but Not Skeletal Muscle Function in Dystrophic Mice

Duchenne muscular dystrophy (DMD) is a degenerative disorder affecting skeletal and cardiac muscle for which there is no effective therapy. Angiotension receptor blockade (ARB) has excellent therapeutic potential in DMD based on recent data demonstrating attenuation of skeletal muscle disease progre...

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Autores principales: Bish, Lawrence T., Yarchoan, Mark, Sleeper, Meg M., Gazzara, Jeffrey A., Morine, Kevin J., Acosta, Pedro, Barton, Elisabeth R., Sweeney, H. Lee
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120761/
https://ncbi.nlm.nih.gov/pubmed/21731628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020856
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